Branch chain amino acid and melanogenesis
نویسندگان
چکیده
منابع مشابه
Branched Chain Amino Acid Aminotransferase
The kinetics of transamination reactions catalyzed by pig heart “branched chain amino acid” aminotransferase was investigated. The activation of aged preparations by 2mercaptoethanol, previously noted, was associated with increases in both the maximum velocity and enzyme-substrate affinities. This implies a protein conformational change. The sharp pH optimum observed with standard assay conditi...
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PURPOSE OF REVIEW The current review aims to provide an update on the recent biomedical interest in oncogenic branched-chain amino acid (BCAA) metabolism, and discusses the advantages of using BCAAs and expression of BCAA-related enzymes in the treatment and diagnosis of cancers. RECENT FINDINGS An accumulating body of evidence demonstrates that BCAAs are essential nutrients for cancer growth...
متن کاملRegulation of branched-chain amino acid catabolism.
Catabolism of the branched-chain amino acids is regulated in part at the step catalyzed by the branched-chain alpha-ketoacid dehydrogenase complex. Previous work suggests both short-term and long-term control mechanisms are involved in regulation of the kinase responsible for phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex. Recent work of this laborat...
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http://ard.bmj.com/content/early/2010/04/10/ard.2009.120857.full.html Updated information and services can be found at: These include: References http://ard.bmj.com/content/early/2010/04/10/ard.2009.120857.full.html#ref-list-1 This article cites 23 articles, 5 of which can be accessed free at: P<P Published online April 13, 2010 in advance of the print journal. service Email alerting box at the...
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The enzymatic conversions necessary for the catabolism of branched-chain amino acids have been reported to occur in a wide variety of bacteria. However, most studies have been done using several species of Pseudomonas. Pseudomonads are richly endowed with extraordinary nutritional versatility, which enables them to catabolize a diverse array of organic compounds (64), including the branchedchai...
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ژورنال
عنوان ژورنال: Immunopharmacology and Immunotoxicology
سال: 2011
ISSN: 0892-3973,1532-2513
DOI: 10.3109/08923973.2011.631140